BORRELIA BURGDORFERI AND BORRELIA MIYAMOTOI IN ATLANTIC CANADIAN WILDLIFE


Metformin Enhances Antidepressant/Antipsychotic Combination Therapy of Schizophrenia With Comorbid Depression in a Murine Model

Comorbid depressive disorders confound the diagnosis and therapy of schizophrenia.Using a murine model incorporating both MK801 and chronic unpredictable mild stress exposures, we successfully replicated both psychosis and depression.Ex vivo patch clamp recordings and in vivo calcium imaging demonstrated impaired neural activity in the prefrontal c

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MicroRNA-575 targets Derlin 1 to regulate proliferation, migration and invasion of human thyroid cancer cells

Introduction This study was undertaken to examine the expression of miR-575 in thyroid cancer tissues and to explore its therapeutic potential.Material and methods Expression analysis was carried out by qRT-PCR.The MTT assay was used for cell viability.DAPI and annexin V/PI assays were used to detect apoptosis.Wound healing and Transwell assays wer

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